To change the column spacing of the content placeholder in PowerPoint, you can follow these steps:
1. Open your PowerPoint presentation and go to the slide where you want to adjust the column spacing.
2. Select the content placeholder by clicking on it.
3. On the ribbon at the top, click on the "Format" tab.
4. In the "Arrange" group, click on the "Align" dropdown menu.
5. From the dropdown menu, select "Grid Settings".
6. In the "Grid and Guides" dialog box, you can adjust the "Column spacing" value to your desired spacing.
7. Click "OK" to apply the changes.
By adjusting the column spacing, you can customize the layout and appearance of your content in PowerPoint.