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In reference to the production of membrane-bound immunoglobulin, which of the following is mismatched?

a) somatic recomb; Iga and Igb
b) hydrophobic sequence of immunoglobulin heavy chain; carboxy terminus
c) Iga and Igb; transport immunoglobulins to the cell surface
d) leader peptide of heavy and light chains: entry into the ER

User Elston
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Final answer:

Referring to the production of membrane-bound immunoglobulins, mismatched pairs are somatic recombination and IgA and IgB.

So, the correct answer to the question is A) somatic recomb; IgA and IgB.

Step-by-step explanation:

In addressing which of the following is mismatched in reference to the production of membrane-bound immunoglobulin, we have a few components to consider. Membrane-bound immunoglobulins (Ig), such as IgA and IgB, are created through a process known as somatic recombination (somatic recomb), which involves the mutation and recombination of gene segments to produce diverse antibody varieties.

The hydrophobic sequence in immunoglobulin heavy chains targets the protein to the membrane and is typically located at the carboxy terminus. Igα and Igβ (Iga and Igb) are proteins associated with the B cell receptor complex and are essential for the transport of B cell receptors, which include membrane-bound immunoglobulins, to the cell surface. The leader peptide of heavy and light chains plays a crucial role in directing these chains into the endoplasmic reticulum (ER).

The mismatched option here appears to be option a) somatic recomb; IgA and IgB, as somatic recombination is a process that leads to the production of antibody diversity, including that of IgA and IgB, rather than being mismatched with these particular immunoglobulins.

Therefore, the correct answer to the question is a) somatic recomb; Iga and Igb.

User Gesias
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