Question

Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis. Which of the following statements is true?

a) Histone acetylation occurs in the nucleus
b) Cytosolic acetyl-CoA has no impact on histone modification
c) Histone acetylation primarily targets H3K27
d) Arabidopsis lacks histones

Answer 1

Histone acetylation primarily targets H3K27 in Arabidopsis, and it is promoted by cytosolic acetyl-CoA. This process leads to the loosening of nucleosomes and the opening of DNA for transcription.

Step-by-step explanation:

The correct statement is c) Histone acetylation primarily targets H3K27. In Arabidopsis, histone acetylation is promoted by cytosolic acetyl-CoA, and it predominantly occurs at the H3K27 position. Histone acetylation leads to the loosening of nucleosomes and the opening of DNA for transcription. This process is reversible and can be influenced by various enzymes, such as histone acetyltransferases (HAT enzymes) and deacetylases.