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Match the term with its definition.

Localization of genes using microscopy.
Using genetic crosses to determine relative recombination distances.
Using DNA cloning to determine nucleotide sequence distance.
a) Genetic techniques
b) Microscopic analysis
c) Molecular biology methods
d) Bioinformatics approaches

1 Answer

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Final answer:

Cytogenetic mapping involves microscopic analysis to determine the distance between genetic markers, linked to microscopic analysis. Genetic techniques like linkage analysis use genetic crosses to determine recombination distances. DNA sequencing, a molecular biology method, is used in sequence mapping to find nucleotide sequence distances.

Step-by-step explanation:

The various methods used for genome mapping can be matched with their definitions:

  • Localization of genes using microscopy is associated with cytogenetic mapping, which involves the microscopic analysis of stained chromosome sections to determine the approximate distance between genetic markers.
  • Using genetic crosses to determine relative recombination distances corresponds to linkage analysis, which is a genetic technique to estimate the distance between genes on a chromosome by analyzing the frequency of recombination during meiosis.
  • Using DNA cloning to determine nucleotide sequence distance refers to sequence mapping, which is a method within molecular biology that utilizes DNA sequencing technology to create detailed physical maps of the genome.

So, the correct matches are as follows:

  1. Localization of genes using microscopy - b) Microscopic analysis
  2. Using genetic crosses to determine relative recombination distances - a) Genetic techniques
  3. Using DNA cloning to determine nucleotide sequence distance - c) Molecular biology methods

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