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What score (semi-quantitative) is highly suggestive of ATTR?

User Gladiator
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1 Answer

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Final answer:

The question seeks a semi-quantitative score indicative of transthyretin amyloidosis (ATTR), typically a higher score on a given scale in diagnostic tests for ATTR is highly suggestive of the condition.

Step-by-step explanation:

The student is asking about a semi-quantitative score that is highly suggestive of ATTR, which likely refers to transthyretin amyloidosis (ATTR), a medical condition. In the context of ATTR diagnosis, semi-quantitative scoring is used for various tests such as cardiac imaging or biopsies, where different intensities of staining, uptakes, or other measurable traits are assigned numerical values typically on a scale. For example, in a scintigraphy test for cardiac ATTR, a score of 2 or 3 is highly suggestive of ATTR.

In other testing contexts mentioned in the provided information, such as the Apgar score for assessing newborns or outcomes on math tests, a higher score, like scoring in the 90s or 100, represents better performance or condition. Similarly, in molecular biology, peptides with a high score in a MASCOT search, indicating a p-value less than 0.05, are strongly suggestive of a true match.

Therefore, while the specific semi-quantitative scoring rubric for ATTR diagnosis was not provided, typically, the higher the score on the respective test (similar to a higher Apgar score indicating normal newborn health or a high peptide score indicating a true match), the more suggestive it is of ATTR.

User Chris Landeza
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