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At what % of myocardium at risk si revascularization better?

User Beller
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Final answer:

Revascularization is generally considered for significant myocardial at risk and is effective in acute MI situations but does not necessarily improve long-term survival. Cognitive and functional outcomes post-revascularization, as well as the benefits of medical therapy and lifestyle changes, should be taken into account. Cardiac repair through stem cells is a field of ongoing research with potential future implications.

Step-by-step explanation:

The effectiveness of revascularization procedures like coronary bypass surgery is dependent on several factors, including the percentage of myocardium at risk. The decision to perform revascularization is typically made when there is significant blockage that threatens a large portion of the myocardium. Such procedures are evidently efficient in treating patients experiencing an acute myocardial infarction (MI), but they do not necessarily increase longevity. In cases of underlying atherosclerosis, which significantly raises the risk of myocardial infarction or stroke, surgery may be advised to expand narrowed arteries or graft vessels to bypass blockages.

It is also important to note that while revascularization can be critical in acute MI situations, its advisability in patients with stable but reduced cardiac capacity is less clear. Post-surgical cognitive decline and the long-term success of lifestyle changes and medication should be considered. Long-term behavior modifications to diet and exercise, in combination with medications to manage blood pressure, cholesterol, and clotting, can be equally effective.

Furthermore, the heart's limited capacity to repair itself through mitosis means that after a myocardial infarction, scar tissue often replaces dead cells, which affects the cardiac function. Research into the heart's stem cells and their potential role in cardiac repair is ongoing and may lead to future advances in treatment.

User Gizgok
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