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Partial opioid agonist with action at mu and kappa receptors: A) Naloxone B) Naltrexone C) Buprenorphine D) Methadone

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Final answer:

Buprenorphine is the partial opioid agonist acting on mu and kappa receptors, as opposed to full agonists like Methadone or antagonists like Naloxone and Naltrexone.

Step-by-step explanation:

The partial opioid agonist with action at mu and kappa receptors is C) Buprenorphine. Naloxone and Naltrexone are both opioid antagonists, with Naloxone being used for immediate overdose reversal due to its short action and Naltrexone being effective for long-term maintenance due to its oral bioavailability and long duration. Methadone is a full opioid agonist used in maintenance therapy for opioid dependence due to its long half-life but does not act as a partial agonist like Buprenorphine. Buprenorphine, due to its partial agonist activity, can reduce pain (analgesic effect) without producing the same level of euphoria or respiratory depression as full agonists and is also used in the management of opioid dependence.

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