Question

Finally DNA ligase covalently links the two daughter strands DNA replication often results in two intertwined molecules Intertwined circular molecules are termed ______.These are separated by the action of topoisomerase

Answer 1

Intertwined circular DNA molecules formed during DNA replication are called catenanes, and they are separated by topoisomerase enzyme.

Step-by-step explanation:

During DNA replication, the enzyme DNA ligase plays a crucial role in sealing the gaps between Okazaki fragments on the lagging strand, thereby linking the two daughter strands covalently. The process sometimes results in intertwined DNA molecules, especially with circular DNA. These intertwined circular DNA molecules are referred to as catenanes, which are subsequently separated by the action of the topoisomerase enzyme. Topoisomerase helps in relieving the tension caused by supercoiling during DNA replication by making temporary cuts in the DNA strands, allowing them to untwist and then resealing them.

Learn more about Catenanes