Final answer:
The major hemoglobin found in red cells of patients with sickle cell trait is Hemoglobin A (HbA), which is the normal form of hemoglobin. This allows individuals with sickle cell trait to function without severe symptoms, even though they also produce some Hemoglobin S.
Step-by-step explanation:
The major hemoglobin found in red cells of patients with sickle cell trait is Hemoglobin A (HbA).
Individuals with sickle cell trait have inherited one sickle cell gene (HbS) and one normal gene for hemoglobin (HbA). As a result, the majority of their hemoglobin is normal, allowing for generally typical red blood cell function. The presence of HbA prevents the red blood cells from sickling under most conditions, which is why individuals with sickle cell trait do not exhibit severe symptoms of sickle cell disease. However, they can still produce some Hemoglobin S, the abnormal hemoglobin that causes sickling of red blood cells in low-oxygen environments or under stress, yet it is not present in sufficient amounts to cause the characteristic symptoms of sickle cell anemia.The sickle-shaped cells can then become lodged in narrow blood vessels, blocking blood flow and resulting in various health issues.
Learn more about Sickle Cell Trait