Question

3 The disease metachromatic leukodystrophy is characterized by the buildup of a certain type of lipid, which is toxic

to oligodendrocytes. Predict the effects of this disease. Would it affect the central or peripheral nervous system?
Why?

Answer 1

Metachromatic leukodystrophy affects the central nervous system, specifically targeting oligodendrocytes and the myelin sheath. This leads to impaired signal transmission and neurological symptoms.

Step-by-step explanation:

The disease metachromatic leukodystrophy affects the central nervous system. This is because oligodendrocytes, which are responsible for producing the myelin sheath in the central nervous system, are specifically targeted by the toxic buildup of certain lipids. The myelin sheath is essential for the proper functioning of nerve cells, allowing for efficient transmission of signals. When the myelin sheath is damaged or destroyed, it leads to impaired transmission of signals in the central nervous system, resulting in various neurological symptoms.

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