Final answer:
Methyltransferase is not an important enzyme in DNA replication.
Step-by-step explanation:
Out of the given options, Methyltransferase is not an important enzyme involved in DNA replication. Ligase is responsible for joining Okazaki fragments, Primase synthesizes RNA primers, Topoisomerase relieves the supercoiling of DNA, while Methyltransferase is involved in adding methyl groups to DNA or other molecules.
Learn more about Enzymes in DNA replication