Final answer:
The largest number of enslaved persons were sent to the West Indies from Africa during the transatlantic slave trade.
Step-by-step explanation:
The largest number of enslaved persons from Africa were sent to the West Indies upon leaving Africa. The West Indies, also known as the Caribbean islands, had a high demand for labor on sugar plantations. This demand led to the transatlantic slave trade, where millions of Africans were forcibly transported and enslaved in various parts of the Americas. The Spanish Americas, including countries like Mexico and Peru, also received a significant number of enslaved individuals.
Learn more about Transatlantic Slave Trade