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People such as Etienne Provost, Peter Skene Ogden, and Miles Goodyear came to the region primarily for its resources. These individuals were mountain men who traveled to the American West in search of valuable resources such as furs and pelts. They were known for their skills in trapping beavers, which were highly prized for their luxurious fur. The mountain men played a significant role in the fur trade, which was a major industry in the American West during the early 19th century.

The arrival of mountain men in the region introduced new foods, such as oranges, to the Native Americans there. However, the introduction of old world diseases also had a devastating effect on the Native American population, leading to a significant decline in their numbers. The mountain men did not introduce a horse culture similar to the Plains tribes, as horses were already present in the region before the arrival of Europeans. Christianity was also not introduced to the region by the mountain men, although it would later become a major influence on Native American life through the efforts of missionaries.

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