Answer:
The Paleozoic and Mesozoic eras are different because during the Paleozoic era, life evolved from simple organisms to complex animals like fish and amphibians, and land plants emerged. The Mesozoic era was dominated by reptiles like dinosaurs and pterosaurs, with the appearance of small mammals. The end of the Paleozoic era was marked by a mass extinction event that wiped out many species, and the Mesozoic era ended with the extinction of the non-avian dinosaurs.