Question

Which statement about translation is NOT correct?

a. In order for translation to begin, the small ribosomal subunit must bind to the mRNA and the initiator tRNA, which is bound to methionine.
b. The initial amino acid in a polypeptide is located on the C-terminus.
c. The large ribosomal subunit is responsible for catalyzing peptide bonds between amino acids.
d. Translation is terminated when the mRNA stop codon moves into the ribosomal A site and a release factor binds in the place of tRNA.
e. At the end of termination, the small and large ribosomal subunits separate from one another, and the polypeptide is released

Answer 1

Step-by-step explanation:

b. The initial amino acid in a polypeptide is located on the C-terminus.

This statement is not correct. The initial amino acid in a polypeptide is actually located on the N-terminus.

During translation, the small ribosomal subunit binds to the mRNA and the initiator tRNA, which is bound to methionine. The large ribosomal subunit then joins the complex, and the ribosome moves along the mRNA, reading the codons and adding amino acids to the growing polypeptide chain. The large ribosomal subunit is responsible for catalyzing peptide bonds between amino acids.

Translation is terminated when the mRNA stop codon moves into the ribosomal A site and a release factor binds in the place of tRNA. At the end of termination, the small and large ribosomal subunits separate from one another, and the polypeptide is released.

So, the statement that is NOT correct is b. The initial amino acid in a polypeptide is located on the C-terminus.