Question

Vertebrate adaptive immune systems use clonal selection to recognize and deal with viral infection of a cell. Which of the following best describes the process of clonal selection? A. Recombination generates a diversity of immune cells; cells that react with self proteins are deleted, and cells that bind to an antigen from a pathogen proliferate rapidly. B. Immune cells are generated by meiotic recombination, and cells that recognize self proteins undergo rapid cell division. C. Clonal lineages of the virus are selected by the immune system to undergo expansion. D. Pattern recognition receptor molecules bind to components of the virus known as pathogen-associated molecular patterns and undergo clonal expansion.

Answer 1

A. Recombination generates a diversity of immune cells; cells that react with self proteins are deleted, and cells that bind to an antigen from a pathogen proliferate rapidly.

Step-by-step explanation:

A. Recombination generates a diversity of immune cells; cells that react with self proteins are deleted, and cells that bind to an antigen from a pathogen proliferate rapidly.

Clonal selection is the process by which the immune system produces a large number of B and T cells that specifically recognize and respond to a particular pathogen. During clonal selection, immune cells that have receptors capable of recognizing the pathogen are selectively activated and proliferate to form a population of identical cells, known as a clone.

The immune system generates diverse immune cells through a process of gene rearrangement, known as V(D)J recombination, during their development in the bone marrow and thymus. Immature immune cells undergo a screening process to eliminate cells that react with self-proteins (self-tolerance) and retain those that can bind to foreign antigens.

Once the pathogen enters the body, immune cells with receptors that recognize the pathogen undergo clonal expansion, producing a large number of identical cells that can target the pathogen. These cells then initiate the immune response to eliminate the pathogen.