Answer:
The development of an organism, including a frog, is controlled by the expression of certain genes which code for specific proteins. Malformations in frogs can occur when there is a disruption in the normal expression of these genes or proteins.
For example, exposure to environmental factors such as pollutants or UV radiation can interfere with the normal expression of genes and proteins during frog development, leading to malformations such as extra limbs, missing eyes, or deformed organs.
Additionally, mutations in certain genes can also result in malformations. For instance, mutations in the genes responsible for regulating limb development can cause abnormalities in the number or shape of a frog's limbs.
Therefore, the relationship between genes and proteins is crucial in understanding how malformations occur in frogs, as disruptions in their normal expression can have profound effects on the development of the organism.