Haha, you had a pretty were typo in "acts". But here's my answer!
As a senator from Indiana, Senator Willis may have been influenced by his state's geography, which is located in the Midwestern United States, far from the country's coasts. Because of its inland location, Indiana was less directly affected by the threat of foreign attacks than states on the coasts. This could have led Senator Willis to believe that the United States should not remain neutral in international conflicts and that the country should take a more active role in foreign affairs to promote its interests and security. Additionally, as a representative of the people of Indiana, Senator Willis may have considered the economic impact of the Neutrality Acts on his state, particularly in terms of trade, which could have further shaped his perspective on the issue.