Answer:
In biology, a chromosomal mutation is the mutation of the chromosomal segments of the DNA strands. This can occur when the number of chromosomes or chromosome sets (ploidy) increases or decreases in a genome as well as when changes in chromosomes structure occur. Irregularities or accidents when cell division happens as well as during chromosomal crossing over or fertilization can all be causes of chromosomal mutation.
All types of chromosomes can undergo chromosomal mutation. Chromosomal mutation examples include chromosome deletion, duplication, inversion, and translation. These are known to cause different kinds of genetic and chromosomal mutation diseases.
For instance, chromosomal mutations on chromosome 4 have been investigated and proven to be the source of numerous genetic disorders and even cancer in humans. This includes conditions like narcolepsy and Parkinson’s disease.