448,867 views
43 votes
43 votes
A person has a bone fracture and takes a painkiller that causes blood-vessel constriction. Why might this painkiller actually slow bone healing? Specifically describe how the drug would affect the three stages of bone healing.

User Abel Callejo
by
3.1k points

1 Answer

11 votes
11 votes

Answer:

Explanation:

Painkillers affects the healing of bones negatively and slow down the healing process. One should be careful what class of painkillers one takes for sprains, ruptured tendons and fractures.

Inflammation is one of the major step of the bone healing which is affected by the painkillers like NSAIDs that inhibits COX-2 that is helpful in impair bone fracture due to the stop the endochondral ossification pathway.

painkiller inhibits the important gene expression that leads to slow bone repair.

User Mitchnull
by
3.1k points