Answer:
Ischemic penumbra is a region of the brain that is at risk of being damaged due to decreased blood flow and oxygen supply. This region is filled with cells that are still alive but are deprived of oxygen, and therefore at risk of death if not treated promptly. Factors that contribute to the survival of neurons in the ischemic penumbra include the size of the affected area, how quickly treatment is administered, and the quality of the treatment. If the cells of the penumbra are unable to be preserved, they will undergo necrosis, or cell death. This can lead to permanent brain damage and can affect the individual's cognitive, motor, and sensory functions.