Answer:
The primary cause of disease among the indigenous people was due to the settlers
Step-by-step explanation:
The contact with the settlers had a very big impact on the indigenous people in America because they would come over with disease they contracted on their journey to the new world or diseases from Europe which the indigenous people had never been exposed to before and would wipe out a lot of the indigenous population. This would also cause conflicts between these new settlers and indigenous people later down the road.