Question

Which of the following would be an effect of blocking all the Na+ leak channels in the neuronal membrane.options:a) There would be no effect on theb) It would become more difficult to trigger an action potential.c) It would become easier to trigger an action potential.d) The peak of the action potential would be more positive than normal.

Answer 1

Complete block of sodium channels would be lethal. However, these drugs selectively block sodium channels in depolarized and/or rapidly firing cells, such as axons carrying high-intensity pain information and rapidly firing nerve and cardiac muscle cells that drive epileptic seizures or cardiac arrhythmias.

Answer: C