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in a litter of kittens some of the kittens have coloring that is completely different from their parents what is the explanation for this

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The placement of the genes on the parent chromosones - B.

The reason for this is that if the parents of the kittens are heterozygotic individuals (Pp and Pp). Where P being one colour and p being another colour, it's quite possible that some of their litter have the pp allele combination which in turn could make them a different colour

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