Answer:
The sentence that best interprets the meaning of the boldfaced term is "Its denotation is "personality"; its connotation is "unavoidable."
Step-by-step explanation:
The bolded word "nature" in the sentence "I would like to ask God to give me a different nature, so that I didn't put everyone's back up." can be used with the literary meaning of "personality", when you refer to a person's nature you refer to the way they act which is their personality, then the connotation "unavoidable" refers to the natural and impossible to avoid instinct that makes us act in a specific way.