CHECKPOINT M in the cell cycle is affected by paclitaxel.
Paclitaxel (PTX) is a compound that is sold under the brand name "Taxol" which is used to treat cancer. G1, G2 and M are the 3 checkpoints where all the chromosomes get attached attached to the spindle fibers. Paclitaxel inhibits the assembly and disassembly of the microtubules and prevents the separation of chromosomes during cell division.