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Horses and donkeys can mate, but they produce a mule, which is always a sterile animal. This means that they cannot produce viable offspring and are reproductivelygeographicallytemporallybehaviorally isolated.

User Peter Fine
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reproductively
just took a test and got it right!!!
hope this help y'all :)
(not sure about the spelling)
User Blankface
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Horses and donkeys can mate, but they product a mule which is always a sterile animal. This means that horses and donkeys are reproductively isolated. Two organisms are reproductively isolated if they can not interbreed to produce a viable and fertile offspring. 
User Paulthenerd
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