Go with the order of operations which is PEMDAS
Parenthesis
Exponents
Multiplication
Division
Addition
Subtraction
The first thing you do is the exponents. 4^2=16. 5^3=125.
Your new equation is 125-30/3+16.
Now you do division since there isn't any multiplication. 30/3=10.
Your new equation is 125-10+16.
Addition is your next step. -10+16 is 6.
Your new equation is 125+6.
Your answer is 131.
Ta-da.