The correct answers are the following. First blank: Africa. Second blank: South America.
The two all-water routes to Asia that had been discovered were around the continent of Africa to the east and around the continent of South America to the west.
During the Age of Exploration in the 1500s, powerful European kingdoms invested a lot of money on sending expeditions to explore new sea routes to get to the Indies, and that is how they get to Africa and later, discovered America.
Portugal was very interested in trade and exploration to the degree they had a navigation school. and sent many expeditions overseas. On the other hand, king Fernando de Aragón and Queen Isabella de Castille supported the Christopher Columbus expedition and he and his ships arrived at the Caribean islands in the Americas on October 12, 1492.