Answer:
Sectional disputes dominated debate during the period between the Missouri Compromise of 1820 and the Compromise of 1850 and brought to the Chamber a group of talented legislators and powerful orators. In the Senate, where the Constitution established an equality of states, there existed a delicate balance between North and South, slave and free states. For many years, senators crafted legislation designed to resolve sectional conflicts and avoid secession and civil war. In the 1850s, however, further efforts at compromise failed. The Senate endured a violent and turbulent decade that propelled the nation to the brink of war.
The rapid expansion of the nation, as settlers moved west and new territories applied for statehood, repeatedly raised the issue of slavery. The Constitution allowed slavery to exist in the states but left Congress to decide its status in the territories. The Northern states, having abolished slavery, sought to prevent its spread, while the Southern states, having grown more dependent on slave labor, asserted the rights of Southerners to transport their way of life into the new territories. In 1820 the Missouri Compromise drew a line across the nation at the 36th parallel, above which slavery would be prohibited, and below which it could expand. When the war with Mexico, from 1846 to 1848, resulted in vast new territories in the southwest, the debate over expansion of slavery was renewed.