Answer:
Option (1).
Step-by-step explanation:
Enzymes are the bio-catalyst that can increases the rate of a biochemical reaction without disturbing the reaction equilibrium. Enzymes are specific in their working and works at optimum pH and temperature conditions.
Co factors are non protein part of the enzyme. Co factors are required to increase the reactivity of the substrate so that reactions can increases with great speed.
Thus, the correct answer is option (1).