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What would be the likely outcome if a microbe could prevent the activation of c3 in the complement cascade?

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The likely outcome if a microbe prevents the activation of C3 in the complement cascade would be Inflammation. Inflammation would be the only outcome of complement activation if C3 activation is blocked.
Complement is a system of proteins that can be activated directly by pathogens or indirectly by pathogen-bound antibody, leading to a cascade of reactions that occurs on the surface of pathogens and generates active components with various effector functions.

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