Question

How are primary and vesicular follicles anatomically different?

Answer 1

Primary follicles contain a primary oocyte with a single layer of cuboidal granulosa cells, while vesicular (secondary) follicles are larger, with multiple granulosa layers, a zona pellucida, and begin to form an antrum filled with follicular fluid.

Step-by-step explanation:

The anatomical differences between primary follicles and vesicular follicles, also known as secondary follicles, arise during folliculogenesis. Primary follicles contain a primary oocyte and are characterized by a single layer of granulosa cells that are cuboidal in shape. As these granulosa cells divide and proliferate, primary follicles develop into secondary follicles, which are notably larger, have multiple layers of granulosa cells, and exhibit the formation of a new outer layer of connective tissue, blood vessels, and theca cells.

In secondary follicles, the primary oocyte secretes a zona pellucida, important for fertilization, and the granulosa cells begin to form an antrum by secreting follicular fluid. Tertiary follicles, which are further developed, have a large, fully formed antrum. Nonetheless, it is crucial to mention that most follicles undergo atresia and do not reach full maturity to ovulate.

Answer 2

Differences is primary has few layers of cuboidal around the large central developing ovum and the vesicular follicle is an around capsule of several layers called the corona radiate. Another, Primary is the one or small number of follicles around the oocyte. While vesicular has a large antrium containing fluid produced by granusule cells, developing oocyte.