Final answer:
The settlers of South Carolina faced numerous challenges such as establishing the colony, inhospitable agricultural conditions, and the transatlantic slave trade. However, the acquisition of land was facilitated by the colony's policies, which is not considered a challenge they faced.
Step-by-step explanation:
Challenges Experienced by the First Settlers in South Carolina
The first settlers in South Carolina faced several challenges, including the establishment of the colony, dealing with the geography, the development of cash crops, and interactions with the indigenous populations. The settlers, who included a significant proportion of enslaved Africans, had to adapt to the harsh conditions of rice and indigo cultivation, which were labor-intensive and led to South Carolina becoming a major port in the transatlantic slave trade.
One challenge that the settlers did not face was the inability to acquire land, as the policies in place allowed men with money and social status to obtain large grants of land, while even those with less wealth could still acquire substantial acreage if they paid their way to the colony.