In the 16th Century Western Europe, the Ottoman Empire and East Asia were living a period of relative peace and truce, having their borders more firmly established.
The end of the Crusades with The siege of Belgrade guaranteed the Christendom territory, on the other hand, in East Asia, the Islamic conquest of Persia and established of Islam, marking an important point in the history of Islam in the east, guaranteed conditions for commercial interactions with the Ottoman Empire.
Western Europe was compelled to search for new commercial routes based on the fact that the Silk Road was controlled by the Ottoman Empire, which was an impediment to European commercial interests, and other Eastern trade routes were not available to the Europeans due to Muslim control.