Answer:
regulating the transport of mRNA to the cytoplasm
Step-by-step explanation:
In eukaryotes, the process of transcription occurs in the nucleus while ribosomes are present in the cytoplasm or on the surface of the rough endoplasmic reticulum. Therefore, the mRNA should leave the nucleus and enter the cytoplasm to serve in the process of protein synthesis. The nuclear envelope contains the nuclear pore complex (NPC). The nuclear pore complex includes several specific nucleoporins embedded in the nuclear envelope.
The NPC serves as the passageway for the transport of mRNA molecules to the cytoplasm. The mature mRNA binds to specific exporter proteins in the nucleus and forms ribonucleoprotein particles that are allowed to pass through the nuclear pore complex.
The middle and carboxyl domain of mRNA exporter binds to the phenylalanine-glycine (FG) repeats in FG nucleoporins to facilitate the mRNA transport. Therefore, the transport of mRNA from the nucleus to the cytoplasm is regulated by the nuclear pore complex. This is how the nuclear membrane is involved in the regulation of gene expression.