Question

Increasing substrate concentration restores enzyme activity that has been blocked by ____(A) a noncompetitive inhibitor only.(B) neither a competitive nor a noncompetitive inhibitor.(C) both a competitive and a noncompetitive inhibitor.(D) a competitive inhibitor only.

Answer 1

Answer: Option D

Explanation: The structure of a competitive inhibitor resembles that of the substrate. It may thus combine with the enzyme to form enzyme-inhibitor (EI) complex rather than enzyme-substrate (ES) complex . However, increasing the substrate concentration and keeping the inhibitor concentration constant restores enzyme activity: as the active site releases the bound inhibitor to bind with the substrate.

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