Question

Prader-Willi (PW) and Angelman syndromes (AS) are imprinting disorders of the same region on chromosome 15. Normally, the genes associated with PW are ________ imprinted (silenced), and the one gene associated with AS is ________ imprinted (silenced). Prader-Willi (PW) and Angelman syndromes (AS) are imprinting disorders of the same region on chromosome 15. Normally, the genes associated with PW are ________ imprinted (silenced), and the one gene associated with AS is ________ imprinted (silenced). paternally; maternally maternally; paternally paternally; paternally maternally; randomly randomly; paternally

Answer 1

Paternally, maternally.

Step-by-step explanation:

Imprinting disorders may be defined as the diseases that occur due to the molecular changes that affect chromosomal regions and genes. The genes will express according to their parent specific manner.

Both the Angelman syndromes and Prader-Willi syndrome are imprinting disorder that occurs due to the changes in chromosome number 15. The Prader-Willi syndrome occurs due to the silencing of the paternal disorder and Angelman syndrome due to the imprinting of the maternal chromosomes.

Thus, the correct answer is option (a).