Answer and Explanation:
Rabies is a disease of animals that may eventually affect humans. The inflammation of the brain caused by Rabies virus is quite serious and usually leads the patient to death
The rabies vaccine (inactivated) is used to prevent rabies. It can be used to prevent rabies before and for a period of time after exposure to the virus, such as a dog bite or bat. The immunity that develops is long lasting after a complete course. Doses are usually given by injection into the skin or muscle. After exposure to vaccination is usually used in conjunction with rabies immunoglobulins. It is recommended that those at high risk of exposure be vaccinated before potential exposure.
Before exposure: pre-exposure vaccination should be offered to individuals at high risk of contamination by the rabies virus and for all those who are permanently at risk, such as: working people in a laboratory for the diagnosis, research, or production of the rabies virus; Veterinarians, veterinary assistants, animal handlers; hunters; professionals who prepare animals for exhibition and cavers (professionals who studies natural cavities like caves).
The vaccine acts by stimulating the body to produce its own protection (antibodies) against the disease. Passive rabies immunization can be done with serum (Intravenous) (heterologous immunoglobulins) or with
human anti-rabies immunoglobulin (homologous immunoglobulins) (vaccines). Serum is obtained from rabies immunized equines and donor immunoglobulins human vaccinated against rabies. Serums are used only in the post-exposure situation concomitantly with the use of rabies vaccine.