Question

As long as ATP is present in an in vitro actin assembly reaction that is at steady state, which of the following will be occurring? Disassembly at the minus end Disassembly at the plus end Assembly at the plus end Treadmilling Assembly at the minus end

Answer 1

- Treadmilling

- Assembly at the plus end

- Disassembly at the minus end

Step-by-step explanation:

As the ATP enters into the vitro actin assembly reaction which is a steady state phase, the filament dynamics progresses into a state of equillibrium where the following happens -

a) The monomer starts disassembling from the negative end.

b) Polymerisation or assembling at the positive end reaches a balance which is then maintained by the ritical concentration of monomers in the cytosol

c) The state phase involving assembly and disassembly is known as ‘treadmilling’.