Question

Disruption of the ________ gene leads to an increase in the number of neurons present in the developing central nervous system of Drosophila Embryos.

a. SHH
b. Ephrin
c. Eph
d. MyoD
e. Notch

Answer 1

The correct answer is option e. "Notch".

Step-by-step explanation:

The Notch gene activity is to regulate both neurogenesis and cell cycle in Drosophila. Notch is a regulator of apoptosis (programmable cell death) during Drosophila embryo development, therefore the disruption of this gene would provoke that no apoptosis take place and an increase the number of neurons in the developing central nervous system. A scientific investigation show that when Numb inhibits Notch signaling cells undergo neuronal differentiation, therefore it is expected that the disruption of Notch would have similar results.