Question

Which of the following statements concerning intracellular receptors is FALSE? a. Their ligands are hydrophobic. b. Most are transcription factors. c. Some are located in the cytosol. d. After binding their ligand, they move out of the cell. e. Some are in the nucleus.

Answer 1

The correct answer is d. After binding their ligand, they move out of the cell

Step-by-step explanation:

Intracellular receptors are present in cytoplasm and mostly on the nucleus. They are called intracellular because they are present inside the cell. Intracellular nuclear receptors are mostly transcription factors which regulate the transcription process after binding with their ligand.

These ligands are hydrophobic molecules such as steroid hormones and thyroid hormones when binds to nuclear receptors cause conformational change in them, then the receptors act as transcriptional factor which binds to regulatory DNA sequence and regulates transcription.

So after binding with their ligand they do not move outside the cell rather move inside the nucleus to regulate transcription.