Question

IP3 is thought to produce its biologic effects by

a) directly activating calmodulin.
b) directly stimulating protein kinase C.
c) promoting release of calcium from intracellular stores into the cytoplasm.
d) activating the alpha subunit of G proteins.
e) both b and c.

Answer 1

The best answer to the question: IP3 is thought to produce its biologic effects by:___, would be, C: promoting release of calcium from intracellular stores into the cytoplasm.

Step-by-step explanation:

The means by which a cell may respond to stimuli generated from the outside of it, be it by a neurotransmitter, or a hormone, or any other substance, is pretty complex, and a ball dance of chemical components. However, there is one pathway of intracellular activation that requires IP3. IP3 (Inositol 1,4,5-triphosphate) is a second messenger, found in the cytoplasm of the cell and which will be in charge of relying signals delivered to the cell through the plasma membrane towards the organelles, and especially the endoplasmic reticulum, where calcium ions are stored. IP3 will bind chemically to its own receptor (IP3R), which is bound to calcium channels in the ER. When IP3 binds to this receptor, the channels will open and the ER will release its stored calcium ions into the cytoplasm.