Answer:
The best answer for the question: Gonadal dysgenesis that results in XY females occurs because of which of the following?, would be, D: Duplication of SOX9 0n chromosome 17.
Step-by-step explanation:
Sexual differentiation is a pretty complex balance between genetics that can be offset given the right circumstances. Essentially, human males should carry the chromosomal combination XY, while females should have the XX combination. And the reproductive organs that evolve from this chromosomal combination, should be accordingly (known as sexual phenotype). However, this is not always the case and there have been cases of males with XX combinations and females with XY. Essentially, what this means is that, given the mutations that are caused by these gene combinations, and the coding proteins that they produce, a personĀ“s genetic sex may not be coherent with the phenotype. In women who present the abnormal combination of XY, and tus present with what is known as gonadal dysgenesis (organs do not express genetic sex), the reason for this comes from the presence of the SRY gene, typical in the XY combination. The presence of this gene will activate the sex-determinant SRY-box9, better known as SOX9, which has the capacity to, if present, cause sex reversal, even in XX females.