Question

Which of the following molecules activate phosphofructokinase 1 (PFK1)?

a. Fructose 2, 6-bisphosphate
b. Citrate
c. ATP
d. Glucagon

Answer 1

a. Fructose 2, 6-bisphosphate

Step-by-step explanation:

Phosphofructokinase 1 is a very important enzyme supplement for life maintenance. This is because this enzyme is one of the main enzymes involved in the recolination of glycolysis, preventing the waste and accumulation of molecules in the body. This enzyme must be activated for its regulatory function to be exerted. The main activator of this enzyme is Fructose 2,6-bisphosphate, but the enzyme can also be activated by AMP.

Answer 2

a. Fructose 2, 6 bisphosphate

Step-by-step explanation:

This molecule acts as an allosteric modulator activating phosphofructokinase 1 (PFK1). It does so by increasing PFK1's affinity for Fructose 6 phosphate and at the same time, decreasing PFK1's affinity for its inhibitors (citrate and ATP).