Question

The presence of Auer rods in the cytoplasm of cells rules out _________

A) ALL
B) AML
C) Myelodysplastic syndrome
D) Acute promyelocytic leukemia
E) None of the above

Answer 1

A) ALL

Step-by-step explanation:

• ALL (acute lymphoblastic leukemia) is a blood cancer where there is an abnormal proliferation of the immature white blood cells called lymphocytes in the bone marrow.
• Auer rods are the cytoplasmic inclusions that are crystalline that are made up of lysosomes that are fused and are enriched with lysosomal enzymes.
• These are rods are formed in the myeloid blast cells in case of AML, myelodysplastic syndromes, and Acute promyelocytic leukemia.
• The Auer rods are not formed during ALL and thus, their presence rules out that the person might be suffering from ALL.