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Which of the following is the type of cell largely responsible for type I hypersensitivity responses?

erythrocyte
mast cell
T lymphocyte
antibody

1 Answer

3 votes

Answer: Mast cell

Step-by-step explanation:

Type 1 hypersensitivity can be defined as an reaction( allergic) which is generated through the re-exposure of the same or specific kind of antigen which is known as allergen.

Type 1 hypersensitivity is different from type II, III, IV hypersensitivity. The exposure to the antigen may be by inhalation, injection and infection.

In this case, the antibody released is IgE. During the time of sensitization, the TgE antibody binds to FCER1 receptors on the surface of mast cell and basophills.

On later exposure to the same allergen anaphylatic degranulation takes place with release of histamines and other chemicals.

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