Answer;
A deletion mutation completely destroys a nucleotide, but substitution mutation replaces a nucleotide, or one amino acid.
Explanation;
- Deletion is an example of a Frame shift mutation, a mutation that shift the reading frame of the genetic message by inserting or deleting a nucleotide.
- A deletion mutation occurs when part of a DNA molecule is not copied during DNA replication. Deletion of a nucleotide in a DNA sequence that causes a frame shift mutation which usually produces a malfunctioning protein.
- Substitution Mutation occurs when one nucleotide base is replaced by another. There are three types of substitution mutation namely; Missense, Nonsense, and Silent mutations.