The statement that is true is A) Roosevelt had already run for a national office before he developed polio.
Franklin D. Roosevelt was diagnosed with polio, a disease that is responsible for causing muscle weakness, when he was 39 years old, that is, in 1921. He developed the disease after falling into the icy waters of the Bay of Fundy while he was sailing. Roosevelt had already started his political career when polio struck. He had run for a seat in the New York State Assembly as part of the Democratic Party in 1910 and he had also been an Assistant Secretary of the Navy from 1913 to 1919. Moreover, Franklin Roosevelt was a vice-presidential candidate in 1920, a year before being diagnosed with polio.