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Multiple sclerosis is an autoimmune disorder of nerve cells of spinal cord and brain. It is caused due to destructive immune response of body against covering of nerve cells . The axons of nerve cells are covered by a myelin-sheath, which provides insulation to the nerve cells and speeds up the rate of nerve transmission.
In healthy nerves, axons are insulated properly with myelin sheath and these nerve cells will perform perform proper function. In nerves affected with multiple sclerosis, nerve axons are demyelinated as the myelin sheath is damaged. It leads to impairment in signal transduction and results muscle pain, needles sensation, and deficiency in cognition, movement, or sensation.